Ir. Mccoll et al., LOW-TEMPERATURE PLASMA-ASSISTED CHEMICAL-VAPOR-DEPOSITION OF AMORPHOUS-CARBON FILMS FOR BIOMEDICAL-POLYMERIC SUBSTRATES, DIAMOND AND RELATED MATERIALS, 3(1-2), 1994, pp. 83-87
Preliminary results have been obtained on the biocompatibility of amor
phous carbon hydrogen (alpha C:H) coatings deposited on polystyrene. D
eposition was carried out at low substrate temperatures using pulsed r
.f. plasma-assisted chemical vapour deposition from a methane-hydrogen
gas mixture. Cytotoxicity tests using a standard cell line indicate a
high degree of biocompatibility. Specifically, alpha C:H is not toxic
to cells, appears to increase cell attachment and affords normal cell
growth rates. Wear and other tests have revealed no significant diffe
rences between these alpha C:H coatings and those deposited on a stain
less steel at a higher substrate temperature, except for a more pronou
nced surface texture. However, position in the r.f. plasma was found t
o be critical for the deposition of good, adherent low temperature coa
tings.