ELEMENT VARIATIONS IN PREGNANT AND NONPREGNANT FEMALE RATS ORALLY INTOXICATED BY ALUMINUM LACTATE

Pregnant or nonpregnant female rats were orally intoxicated by aluminu m lactate (400 mg Al/kg/d) from d 0-19 of gestation to determine the t reatment's influence on element variations in the females and their fe tuses. The aluminum levels of plasma, liver, spleen, and kidneys were significantly higher in treated pregnant rats than nonpregnant female rats. Differences of P, Ca, Cu, Zn, or Mg levels were observed among t he four groups of female rats in the tissues and plasma. The aluminum content of the 20-d-old fetuses did not significantly differ between t he treated and control groups. On the contrary, calcium and magnesium levels in the whole fetuses from treated or nontreated dams are signif icantly different.