J. Rorvik et al., TRANSRECTAL ULTRASONOGRAPHY TO ASSESS LOCAL EXTENT OF PROSTATIC-CANCER BEFORE RADICAL PROSTATECTOMY, British Journal of Urology, 73(1), 1994, pp. 65-69
Objective To evaluate transrectal ultrasonography (TRUS) with a 7 mHz
rotating probe as a staging procedure in 33 patients with localized pr
ostatic carcinoma. Patients and methods The ultrasound scans were comp
ared to histopathological whole-mount step sections of the surgical sp
ecimens. Twenty-five of the patients had tumours with pathological sta
ge T3 (pT3) and eight had tumours with stage pT2 giving a prevalence o
f extracapsular growth of 0.76. Results The overall sensitivity, speci
ficity, positive and negative predictive values for detection of extra
capsular tumour growth by TRUS of prostatic cancer were found to be 0.
68, 0.63, 0.85 and 0.38, respectively. Six tumours showed solely micro
scopic foci of extracapsular tumour growth. Conclusion This technique
gives a high percentage of both understaging (32%) and overstaging (37
%) and therefore TRUS is an unreliable tool in the staging protocol pr
ior to radical prostatectomy.