EXPRESSION OF 25(OH) VITAMIN-D-3 24-HYDROXYLASE GENE IN GLIAL-CELLS

Authors
NAVEILHAN P NEVEU I BAUDET C OHYAMA KY BRACHET P WION D
Citation
P. Naveilhan et al., EXPRESSION OF 25(OH) VITAMIN-D-3 24-HYDROXYLASE GENE IN GLIAL-CELLS, NeuroReport, 5(3), 1993, pp. 255-257
Citations number
22
Categorie Soggetti
Neurosciences
Journal title
NeuroReport → ACNP
ISSN journal
09594965
Volume
5
Issue
3
Year of publication
1993
Pages
255 - 257
Database
ISI
SICI code
0959-4965(1993)5:3<255:EO2V2G>2.0.ZU;2-C
Abstract
THE expression of the 25(OH) vitamin D-3 24-hydroxylase gene was studi ed in C6 glioma and rat primary glial cell culture. The expression of the 25(OH)D-3 24-hydroxylase gene was not detected in C6 glioma or gli al cells cultured in a serum-free medium. However, the 25(OH)D-3 24-hy droxylase mRNA was induced in a dose-dependent manner in cells treated with 1,25(OH)(2)D-3. These findings provide further evidence for an i nvolvement of vitamin D-3 metabolites in brain function.