2 NEW ANTIINFLAMMATORY ELEMANOLIDES FROM CENTAUREA-CHILENSIS

Authors
NEGRETE RE BACKHOUSE N CAJIGAL I DELPORTE C CASSELS BK BREITMAIER E ECKHARDT G
Citation
Re. Negrete et al., 2 NEW ANTIINFLAMMATORY ELEMANOLIDES FROM CENTAUREA-CHILENSIS, Journal of ethnopharmacology, 40(3), 1993, pp. 149-153
Citations number
17
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences
Journal title
Journal of ethnopharmacology → ACNP
ISSN journal
03788741
Volume
40
Issue
3
Year of publication
1993
Pages
149 - 153
Database
ISI
SICI code
0378-8741(1993)40:3<149:2NAEFC>2.0.ZU;2-K
Abstract
Two previously undescribed elemanolide esters, the 2-methylpropanoate and 2-methyl-2-propenoate of 11,13-dehydromelitensin, were isolated in the course of a bioassay-guided fractionation from the aerial parts o f Centaurea chilensis Hook. et Am., used traditionally to treat 'gout and rheumatism'. The mixture of both substances exhibits antiinflammat ory activity in the carrageenan-induced paw edema assay.