BIOMEDICAL TRACERS - STUDY OF THE PROPERT IES OF FE3BTMP

Authors
VINCENS M MOLLIER H NAINI A TOULHOAT C VIDAL M FERRETTI G GRAND S LEBAS JF PASQUALINI R
Citation
M. Vincens et al., BIOMEDICAL TRACERS - STUDY OF THE PROPERT IES OF FE3BTMP, Bulletin de la Societe chimique de France, 130(6), 1993, pp. 822-831
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear",Biology,Chemistry
Journal title
Bulletin de la Societe chimique de France → ACNP
ISSN journal
00378968
Volume
130
Issue
6
Year of publication
1993
Pages
822 - 831
Database
ISI
SICI code
0037-8968(1993)130:6<822:BT-SOT>2.0.ZU;2-R
Abstract
The complex ene-1,2,4,5-tetra(methylene-phosphonato)triferrate III 4, Fe3BTMP, is a contrast agent for liver MRI (magnetic resonance imaging ). The stoichiometries 1:1 and 3:1 were found for FeBTMP 3 and Fe3BTMP 4 using polarography and P-31 NMR. At physiological pH and in aqueous solution these complexes are more stable than FeTTMP (5') and as stab le as FeN3TMP (6'). It was found that 3 and 4 are polymers with linear and polydimensional structures respectively.