CHEMOTHERAPEUTICAL CONTROL OF HELMINTH IN FECTIONS IN FARM-ANIMALS - SURVEY OF THE SITUATION IN HUNGARY

Chemotherapeutical preparations against Trematodes, Cestodes and Nemat odes have been summarized according to their chemical structure (Table s 1 to 4). Thereafter preparations, as well as effective agents, regis tered in Hungary, have been reviewed that can be used for preventive o r therapeutical purposes against the most important helminthoses of ca ttle, sheep and goats (Tables 5 to 9), swine (Tables 10 to 11), horses (and donkeys) (Table 12) and poultry (Table 13). First of all, differ ent kinds of benzimidazoles, salicylanilides, imidazothiazoles and ave rmectins have been dealt with. Applicability of different anthelmintic s in the control of certain helminthoses - i. e. diseases caused by fl ukes (Table 6), tapeworms (Table 7), gastrointestinal Nematodes (Table 8), lungworms (Table 9) - has been evaluated with special reference t o the differences in the potency spectrum. Supply of drug formulations that can be used for the treatment of individual farm animal species has been demonstrated (Table 14). Intraruminal ''bolus'' preparations have briefly been reviewed (Table 15). Withdrawal period for consumpti on of food determined for the most important anthelmintics have also b een summarized (Table 16). Finally, mechanisms of the development of r esistance against the anthelmintics have been reviewed together with t he measures proposed for the prevention of drug resistance.