Since preoperative staging of rectal tumors is important in planning t
reatment, we evaluated transrectal ultrasound (TRUS) staging of rectal
neoplasms. In 35 consecutive rectal tumors, we compared TRUS staging
results with final pathologic staging. TRUS predicted the degree of tu
rner invasion in 19 of 24 patients (79%) and the presence or absence o
f lymph node metastasis in 11 of 15 patients (73%). TRUS overestimated
the degree of tumor invasion in four patients (17%) and underestimate
d invasion in one patient (4%). The depth of tumor invasion was correc
tly predicted in all 14 tumors located within 6 cm from the anal verge
, but, beyond 6 cm, only 5 of 10 tumors (50%) were staged correctly (p
= 0.005). In the group of 11 patients who underwent preoperative radi
otherapy, pretreatment TRUS predicted the depth of tumor invasion in o
nly six patients (55%) and overestimated tumor invasion in five patien
ts (45%), suggesting that nearly half of these tumors were downstaged
by radiotherapy. TRUS accurately predicts the degree of tumor invasion
, especially in tumors closer to the anal verge, allowing for better t
reatment planning in patients with low to middle rectal neoplasms.