APPEARANCE OF ANTI-NUCLEOSOME ANTIBODIES PRECEDES THE APPEARANCE OF ANTI-DOUBLE STRAND DNA AND ANTI-HISTONES DURING MURINE LUPUS

Authors
AMOURA Z CHABRE H BACH JF JACOB L
Citation
Z. Amoura et al., APPEARANCE OF ANTI-NUCLEOSOME ANTIBODIES PRECEDES THE APPEARANCE OF ANTI-DOUBLE STRAND DNA AND ANTI-HISTONES DURING MURINE LUPUS, La Revue de medecine interne, 14(10), 1993, pp. 980-980
Citations number
NO
Categorie Soggetti
Medicine, General & Internal
Journal title
La Revue de medecine interne → ACNP
ISSN journal
02488663
Volume
14
Issue
10
Year of publication
1993
Pages
980 - 980
Database
ISI
SICI code
0248-8663(1993)14:10<980:AOAAPT>2.0.ZU;2-A
Abstract
Collected samples serum of 30 MRL lpr/lpr and 15 MRL MP +/ + were test ed by ELISA on purified mononucleosomes and its individual components, dsDNA and histones. Anti-mononucleosome antibodies can be detected as early as 10 and 23 week of age for MRL lpr/lpr and MP +/ +, respectiv ely, and arose before anti-dsDNA and anti-histone antibodies.