MALE-STERILITY DUE TO BILATERAL CONGENITA L APLASIA OF THE VASA DEFERENTIA AS CLINICAL FORM OF CYSTIC-FIBROSIS

We investigated clinical data, sweat electrolytes and cystic fibrosis (CF) mutations in twelve patients with congenital bilateral aplasia of vasa deferentia (CBAVD) to debate arguments for diagnosing CF. Sweat chloride concentration was definitely raised in four patients. Three p atients are CF compound heterozygotes, Six patients are CF heterozygot es. This result reinforces the hypothesis that white males with CBAVD might have a mild form of CE.