PRESYMPTOMATIC DETECTION OF FAMILIAL POLY POSIS-COLI

Authors
DUCROIX JP LENAERTS C MILAZZO S DUPAS JL OLSCHWANG S LAFONT B SMAIL A BAILLET J PUISSAN C
Citation
Jp. Ducroix et al., PRESYMPTOMATIC DETECTION OF FAMILIAL POLY POSIS-COLI, La Revue de medecine interne, 14(10), 1993, pp. 983-983
Citations number
NO
Categorie Soggetti
Medicine, General & Internal
Journal title
La Revue de medecine interne → ACNP
ISSN journal
02488663
Volume
14
Issue
10
Year of publication
1993
Pages
983 - 983
Database
ISI
SICI code
0248-8663(1993)14:10<983:PDOFPP>2.0.ZU;2-8
Abstract
In familial adenomatous polyposis coli (APC) it is possible to detect APC carriers either by research of bilateral congenital hypertrophy of the retinal pigment epithelium (CHRPE) or by genetic diagnosis (APC g ene is localized in 5q21). These detections were performed in 33 patie nts of four families with the same positivity for genetic typing (11 p atients) or for CHRPE (11 patients) which thus avoided annual coloscop y.