R. Marechaud et al., CORTICOTROPH MACROADENOMA - CLINICAL, HOR MONAL, RADIOLOGICAL AND IMMUNOCYTOCHEMICAL STUDY OF 6 CASES, La Revue de medecine interne, 14(10), 1993, pp. 989-989
We report 6 cases of corticotroph macroadenomas which show heterogenei
ty of clinical and biological features (from Cushing's syndrome to sil
ent adenoma) and heterogeneity of immunocytochemical staining. One pat
ient reported on had skin hyperpigmentation and ACTH hypersecretion wi
thout clear abnormal adrenocortical function ; we believe that this pa
tient's plasma contained ACTH with very low bioactivity.