Urgent/emergent percutaneous transvenous mitral commissurotomy (PTMC)
was performed in 10 patients (two men and eight women, aged 21 to 60 y
r). All patients had arterial hypoxemia and four required mechanical r
espirators. PTMC was performed in the semi-recumbent position in four
patients. The seven patients with pliable valves (group 1) achieved go
od hemodynamic and echocardiographic results after PTMC, but one died
2 wk later because of sepsis complicating preexisting pneumonitis. The
two pregnant patients uneventfully delivered normal babies at term. T
here was continued clinical improvement in the six surviving patients
at last follow-up at 11 to 39 mon (median 26). Of the three patients w
ith calcified valves and severe subvalvular lesions (group 2), the pre
moribund patient in whom last-resort PTMC created severe mitral regurg
itation died 3 days later of multiple organ failure. The other two pat
ients underwent mitral valve replacement 1-6 days later because of lac
k of clinical improvement due to creation of severe mitral regurgitati
on and ineffective mitral valve dilation, respectively. In conclusion,
urgent/emergent PTMC is feasible and safe. However, its outcomes are
dictated by the status of diseased mitral valve and coexisting illness
. (C) 1994 Wiley-Liss, Inc.