A HUMAN CDNA-ENCODING THE HOMOLOG OF NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B13

Authors
PATA I TENSING K METSPALU A
Citation
I. Pata et al., A HUMAN CDNA-ENCODING THE HOMOLOG OF NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B13, Biochimica et biophysica acta, N. Gene structure and expression, 1350(2), 1997, pp. 115-118
Citations number
19
Categorie Soggetti
Biology,Biophysics,"Biothechnology & Applied Migrobiology
Journal title
Biochimica et biophysica acta, N. Gene structure and expression → ACNP
ISSN journal
01674781
Volume
1350
Issue
2
Year of publication
1997
Pages
115 - 118
Database
ISI
SICI code
0167-4781(1997)1350:2<115:AHCTHO>2.0.ZU;2-M
Abstract
A cDNA encoding the human homologue of bovine NADH:ubiquinone oxidored uctase (complex I of mitochondrial respiratory chain) subunit B13 has been isolated. The clone contains an open reading frame of 348 bp, 23 bp of 5'-untranslated sequence (UTR) and a long 3'UTR of 1088 bp. The deduced amino-acid sequence is 87% identical to bovine B13, Human B13 mRNA expression was observed in all tissues examined with highest leve ls in heart, skeletal muscle, and brain. Southern analysis of human ge nomic DNA revealed the presence of multigene family.