MOLECULAR-CLONING AND EXPRESSION OF A NOVEL STAPHYLOCOCCUS-AUREUS ANTIGEN

Authors
RIENECK K RENNEBERG J DIAMANT M GUTSCHIK E BENDTZEN K
Citation
K. Rieneck et al., MOLECULAR-CLONING AND EXPRESSION OF A NOVEL STAPHYLOCOCCUS-AUREUS ANTIGEN, Biochimica et biophysica acta, N. Gene structure and expression, 1350(2), 1997, pp. 128-132
Citations number
15
Categorie Soggetti
Biology,Biophysics,"Biothechnology & Applied Migrobiology
Journal title
Biochimica et biophysica acta, N. Gene structure and expression → ACNP
ISSN journal
01674781
Volume
1350
Issue
2
Year of publication
1997
Pages
128 - 132
Database
ISI
SICI code
0167-4781(1997)1350:2<128:MAEOAN>2.0.ZU;2-B
Abstract
A novel gene encoding an antigen from Staphylococcus aureus was isolat ed from an expression library by screening with antisera from patients with deep Staphylococcus aureus infections. In one positive clone an open reading frame, named ORF-2, was identified. Recombinant ORF-2 pro tein reacted with human immune serum. ORF-2 was shown to be present in other Staphylococcus aureus strains, but not in related species.