TRANSIENT HEMIPARESIS ASSOCIATED WITH MONOCLONAL CD3 ANTIBODY (OKT3) THERAPY

Authors
OSTERMAN JD TRAUNER DA REZNIK VM LEMIRE J
Citation
Jd. Osterman et al., TRANSIENT HEMIPARESIS ASSOCIATED WITH MONOCLONAL CD3 ANTIBODY (OKT3) THERAPY, Pediatric neurology, 9(6), 1993, pp. 482-484
Citations number
18
Categorie Soggetti
Neurosciences,Pediatrics
Journal title
Pediatric neurology → ACNP
ISSN journal
08878994
Volume
9
Issue
6
Year of publication
1993
Pages
482 - 484
Database
ISI
SICI code
0887-8994(1993)9:6<482:THAWMC>2.0.ZU;2-B
Abstract
OKT3 therapy for prevention or reversal of allograft rejection has bee n associated with a constellation of acute systemic side effects, defi ned as an OKT3 first-dose reaction. Specific neurologic syndromes, inc luding aseptic meningitis and diffuse encephalitis, have also been obs erved. This report describes a 12-year-old girl with steroid-resistant renal allograft rejection who developed hemiparesis associated with i nitiation of OKT3 therapy.