Malignant tumour arising in chronic congenital or acquired lymphedema
is a rare medical condition. However it must be well known because of
the usual severity of these highly malignant neoplams. Stewart-Treves
angiosarcoma is the most frequent tumour: it is a vascular malignant t
umour, which mostly occur in post-surgical or radiotherapic lymphedema
for breast cancer. It differs from secondary metastasis arising in ly
mphedema although the clinical and histological appearance is often ve
ry close. Other tumours can grow on this ground: Kaposi's sarcoma, squ
amous cell carcinoma, malignant lymphoma, melanoma. On the pathogenic
point of view, many factors converge to this tumoral occurence: lympha
tic stasis and the reorganization of the conjonctival tissue that it w
ill entail, the local immunodeficiency, and also systemic factors as a
general immunodeficiency or viral potentially oncogenic infections su
ch as papillomavirus. In practice, the prevention of lymphedema, the r
egular monitoring of constitued lymphedemas, the hygienic and preventi
ve behaviours of infections are the best arrangements to avoid this tu
moral occurence.