The activity of three urinary enzymes, alkaline phosphatase (ALP), asp
artate aminotransferase (AST), and N-acetyl-beta-D-glucosaminidase (NA
G), was evaluated in 71 adult owl monkeys. Fifty-six animals had norma
l renal function, while 15 had evidence of renal dysfunction. Urinary
enzyme: urinary creatinine ratios (U(E): U(Cr)) were also determined.
The activity for NAG was similar to that of other species, while ALP a
nd AST were higher. Regression analyses revealed that urinary enzymes
and U(E):U(Cr) were significantly correlated (P less-than-or-equal-to
0.0001) with indices of renal damage and could identify active renal d
isease.