DIASTEREOCONTROL IN THE ASYMMETRIC DIHYDROXYLATION OF CHIRAL 3-ALKENYL-4,5-DIHYDROISOXAZOLES

Authors
WADE PA COLE DT DAMBROSIO SG
Citation
Pa. Wade et al., DIASTEREOCONTROL IN THE ASYMMETRIC DIHYDROXYLATION OF CHIRAL 3-ALKENYL-4,5-DIHYDROISOXAZOLES, Tetrahedron letters, 35(1), 1994, pp. 53-56
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
1
Year of publication
1994
Pages
53 - 56
Database
ISI
SICI code
0040-4039(1994)35:1<53:DITADO>2.0.ZU;2-K
Abstract
Catalytic asymmetric dihydroxylation of 4 afforded virtually one diast ereomer using (DHQD)(2)-PHAL as a chiral auxiliary (matched pair; 96% d.e.); the other diastereomer was heavily predominant with (DHQ)(2)-PH AL as the chiral auxiliary (mismatched pair; 90% d.e.).