RESOLUTION OF ALLYLIC ALCOHOLS VIA COPPER(I) COMPLEXES WITH A CHIRAL DIAMINE

Authors
CUCCIOLITO ME RUFFO F VITAGLIANO A FUNICELLO M
Citation
Me. Cucciolito et al., RESOLUTION OF ALLYLIC ALCOHOLS VIA COPPER(I) COMPLEXES WITH A CHIRAL DIAMINE, Tetrahedron letters, 35(1), 1994, pp. 169-170
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
1
Year of publication
1994
Pages
169 - 170
Database
ISI
SICI code
0040-4039(1994)35:1<169:ROAAVC>2.0.ZU;2-T
Abstract
By using the Corey diamine [(2,4,6-trimethylphenyl)methyl]-1,2-diamino ethane, Copper(I) olefin complexes are prepared. When the olefin is a racemic allylic alcohol, selective coordination of one enantiomer is o bserved Cleavage with aqueous HCl or NaCN allows a two-steps resolutio n affording excellent enantiomeric excess.