NETROPSIN SUPPRESSES DEVELOPMENT OF INTRACELLULAR SERINE PROTEINASE ACTIVITY DURING POSTEXPONENTIAL GROWTH OF BACILLUS-MEGATERIUM

Authors
KUCEROVA H CHALOUPKA J
Citation
H. Kucerova et J. Chaloupka, NETROPSIN SUPPRESSES DEVELOPMENT OF INTRACELLULAR SERINE PROTEINASE ACTIVITY DURING POSTEXPONENTIAL GROWTH OF BACILLUS-MEGATERIUM, Folia microbiologica, 38(5), 1993, pp. 360-362
Citations number
10
Categorie Soggetti
Microbiology,"Biothechnology & Applied Migrobiology
Journal title
Folia microbiologica → ACNP
ISSN journal
00155632
Volume
38
Issue
5
Year of publication
1993
Pages
360 - 362
Database
ISI
SICI code
0015-5632(1993)38:5<360:NSDOIS>2.0.ZU;2-4
Abstract
The antibiotic netropsin decreased only slightly the exponential growt h rate in a medium with mineral salts and glucose but its effect was i ncreased during postexponential growth. Protein turnover and the basal intracellular serine proteinase (ISP) activity in the crude cytoplasm ic fraction were not significantly affected by netropsin during expone ntial growth. However, ISP activity increased during postexponential g rowth and its rise was inhibited by the antibiotic. The population in the postexponential phase was not committed to sporulation.