Y. Haikel et al., IN-VITRO EFFICIENCY OF ENDODONTIC IRRIGATION SOLUTIONS ON PROTEIN DESORPTION, International endodontic journal, 27(1), 1994, pp. 16-20
The use of irrigating solutions is widely accepted as a necessary adju
nct to biomechanical preparation to obtain adequate cleansing of the r
oot canal system. In this study, the efficiency of three solutions was
tested in an in vitro experimental system for the removal of protein
from apatite surfaces: Salvizol (a bis-dequalinium acetate solution) a
nd sodium hypochlorite at 0. 5, 1, 3 and 6% at pH 7.4 and 11.5. Buffer
ed Tris-HCl solutions at pH 7.4 and 11.5 were used as controls. All ch
emicals showed rapid kinetic effects since no variation of the process
could be detected after 5 min. Salvizol was the least efficient solut
ion since it induced only a 2% protein desorption. Sodium hypochlorite
efficiency increased with concentration to reach a 70% protein desorp
tion from the apatite surface. In general, alkaline solutions were mor
e efficient than buffered ones, and the ionic strength did not appear
to have a major effect on the protein desorption process.