COLOCALIZATION OF FOS- AND GLUCOCORTICOID RECEPTOR-IMMUNOREACTIVITIESIS PRESENT ONLY IN A VERY RESTRICTED POPULATION OF DORSAL HORN NEURONS OF THE RAT SPINAL-CORD AFTER NOCICEPTIVE STIMULATION

Authors
CINTRA A MOLANDER C FUXE K
Citation
A. Cintra et al., COLOCALIZATION OF FOS- AND GLUCOCORTICOID RECEPTOR-IMMUNOREACTIVITIESIS PRESENT ONLY IN A VERY RESTRICTED POPULATION OF DORSAL HORN NEURONS OF THE RAT SPINAL-CORD AFTER NOCICEPTIVE STIMULATION, Brain research, 632(1-2), 1993, pp. 334-338
Citations number
31
Categorie Soggetti
Neurosciences
Journal title
Brain research → ACNP
ISSN journal
00068993
Volume
632
Issue
1-2
Year of publication
1993
Pages
334 - 338
Database
ISI
SICI code
0006-8993(1993)632:1-2<334:COFAGR>2.0.ZU;2-3
Abstract
Immunocytochemical techniques were used to study the colocalization of proto-oncogene c-fos protein (Fos)-like immunoreactivity and of gluco corticoid receptor immunoreactivity in the spinal cord dorsal horn of adult male rats after nociceptive stimulation. About 5-10% of the stim ulus evoked Fos-immunoreactive profiles colocalized glucocorticoid rec eptor immunoreactivity. The results suggest the possibility of a corti costeroid action in a small neuronal population of the dorsal horn imp licated in processing nociceptive inputs.