Eight healthy male volunteers took part in a randomised double blind s
tudy of the effects of 2 g dried ginger or placebo capsules on platele
t function. Bleeding time, platelet count, thromboelastography and who
le blood platelet aggregometry were performed before, 3 h, and 24 h af
ter the capsules. There were no differences between ginger and placebo
in any of the variables measured. It is concluded that the effect of
ginger on thromboxane synthetase activity is dose dependent, or only o
ccurs with fresh ginger, and that upto 2 g of dried ginger is unlikely
to cause platelet dysfunction when used therapeutically.