In a 65-year-old patient with slowly progressive myelopathy of the low
er spinal cord MRI revealed slight thickening of the conus medullaris
and discrete serpiginous areas of low signal intensity in contact to t
he surface of the myelon. The T2-weighted axial images demonstrated a
zone of high signal intensity within the center of the lumbosacral cor
d. These findings corresponded to the results of autopsy: cord enlarge
ment, dilatation of wallthickened and partially thrombosed pial veins,
edema, damage of the myelin sheath with development of foam cells, ar
eas of hemorrhage and necrosis. Although myelography and spinal digita
l subtraction angiography had been normal in this case we assume that
perhaps a spinal dural av-fistula may have been the cause of MR- and p
athological findings which indicate an angiodysgenetic myelomalacia (M
orbus Foix-Alajouanine). The pathogenesis of spinal dural av-fistulas
is discussed in order to explain why angiography has been negative.