Glomus tumors are uncommon, benign soft tissue tumors that can occur i
n a familial or sporadic pattern. Only 15 pedigrees have been reported
to date. We report a family with three generations developing multipl
e glomus tumors of the skin. Although controversy exists over pattern
of inheritance, review of the published pedigrees plus this additional
one suggests an autosomal dominant inheritance with incomplete penetr
ance and variable expressivity.