COMBINATION EFFECT ON HIV-INFECTION IN-VITRO OF SOLUBLE CD4 AND HIV-NEUTRALIZING ANTIBODIES

Authors
HANSEN JES SORENSEN AM OLOFSSON S OSINAGA E ROSETO A
Citation
Jes. Hansen et al., COMBINATION EFFECT ON HIV-INFECTION IN-VITRO OF SOLUBLE CD4 AND HIV-NEUTRALIZING ANTIBODIES, Archives of virology, 134(1-2), 1994, pp. 179-184
Citations number
14
Categorie Soggetti
Virology
Journal title
Archives of virology → ACNP
ISSN journal
03048608
Volume
134
Issue
1-2
Year of publication
1994
Pages
179 - 184
Database
ISI
SICI code
0304-8608(1994)134:1-2<179:CEOHIO>2.0.ZU;2-#
Abstract
In combination with HIV gp120 V3-loop antibody, two carbohydrate speci fic neutralizing antibodies (83D4 and 2G12) had a synergistic neutrali zing effect on HIV infection. However, sCD4 and an antibody which bloc ks gp 120/CD4 binding (1B1) both displayed antagonism.