J. Reisch et al., ACETYLENIC CHEMISTRY .26. ONE-POT SYNTHESIS OF 1,3-DIALKYLATED DERIVATIVES OF QUINAZOLINONE AND ITS AZA-ANALOG VIA MITSUNOBU REACTION, Monatshefte fuer Chemie, 124(11-12), 1993, pp. 1217-1220
Quinaozolin-2,4-(1H,3H)-dione (1), 6,7-dimethoxy-quinazolin-2,4-(1H,3H
)-dione (2), and 2,3,4-tetrahydro-2,4-dioxo-pyrido[2,3-d]pyrimidine (3
) were subjected to Mitsunobu conditions using propinol to give the 1,
3-dialkylated derivatives 4, 5, and 6.