A schizophrenic patient receiving neuroleptic treatment developed para
lytic ileus followed by the neuroleptic malignant syndrome (NMS). The
patient had previously experienced two NMS episodes, one of which was
also accompanied by paralytic ileus. It is suggested that paralytic il
eus can occur as a prodromal symptom of NMS. Therefore, if this sympto
m is observed in patients receiving neuroleptic treatment, especially
those with a past history of NMS, careful attention should be paid to
the possible development of NMS.