The always growing number of cephalosporins constitutes a significant
part of the betalactam antibiotics. Depending on antibacterial spectru
m and in vitro activity, different groups, e. g. the ''cefuroxime-grou
p'' and the ''cefotaxime-group'' have been defined. Based on epidemiol
ogic and comparative in vitro data, the present review offers some gui
dance where the less expensive cephalosporins of the ''cefuroxime-grou
p'' may still be clinically useful.