DEGRADATIVE ROUTES TO ELECTROPHILIC CD-SUBSTRUCTURES OF TAXOL

Authors
DIGRANDI MJ COBURN CA ISAACS RCA DANISHEFSKY SJ
Citation
Mj. Digrandi et al., DEGRADATIVE ROUTES TO ELECTROPHILIC CD-SUBSTRUCTURES OF TAXOL, Journal of organic chemistry, 58(27), 1993, pp. 7728-7731
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
58
Issue
27
Year of publication
1993
Pages
7728 - 7731
Database
ISI
SICI code
0022-3263(1993)58:27<7728:DRTECO>2.0.ZU;2-A
Abstract
Various electrophilic derivatives containing the CD-substructure of ta xol and bearing suitable appendages for joining to potential A-ring sy nthons have been prepared. This chemistry points to the stability of t he oxetane to a variety of reaction conditions.