Nasal passage geometry was measured by acoustic rhinometry in 8 health
y medical students (5 males and 3 females, 21-29 years old; mean age 2
4 years) after 6 min in different postures of head and body. The minim
um cross-sectional area (A-min) and volume between the nostril and 7 c
m posteriorly were measured on both sides. When changing from sitting
to horizontal the total airway dimension (i.e., the sum of A-min for t
he two sides) decreased by about 16% (Mean +/- SD = 0.19 +/- 0.14 cm2)
, and when standing up it increased by about 12% (0.14 +/- 0.13 cm2).
A-min seemed more sensitive than volume to detecting postural changes.
Including the variation between the cavities, the coefficient of vari
ation (CV = SD/Mean) for area was 24.8 +/- 6.7 and for volume 22.4 +/-
6.4 for the 8 subjects. For the total nasal airway passage the corresp
onding figures were 12.9 +/- 3.9 and 10.9 +/- 5.5. These figures are c
onsiderably higher than for subjects measured only in the sitting posi
tion under comparable circumstances. In conclusion, our findings indic
ate a composite response of the nasal cavity mucosa to both systemic (
hydrostatic) and local conditions, probably induced by vascular and cu
taneous reflexes. These factors must be taken into account in studies
of environmental, clinical, and pharmacological conditions.