Arterial casts of human cervical lymph nodes were studied using scanni
ng electron microscopy. Human cervical lymph nodes appear to be much m
ore complex and dense than their animal counterparts. Human lymph node
s have a separate medulla arising from the hilar artery complex and co
rtical structure derived from capillaries. Also present is a previousl
y unknown rosette formation of blood vessels. The possible implication
s of these findings for inflammatory and neoplastic diseases are discu
ssed.