REGULATION OF THE RAFFINOSE PERMEASE OF ESCHERICHIA-COLI BY THE GLUCOSE-SPECIFIC ENZYME IIA OF THE PHOSPHOENOLPYRUVATE - SUGAR PHOSPHOTRANSFERASE SYSTEM

In enteric bacteria, chromosomally encoded permeases specific for lact ose, maltose, and melibiose are allosterically regulated by the glucos e-specific enzyme IIA of the phosphotransferase system. We here demons trate that the plasmid-encoded raffinose permease of enteric bacteria is similarly subject to this type of inhibition.