REED-STERNBERG CELLS AND BYSTANDER LYMPHOCYTES IN LYMPH-NODES AFFECTED BY HODGKINS-DISEASE ARE INFECTED WITH DIFFERENT STRAINS OF EPSTEIN-BARR-VIRUS

Authors
MEGGETTO F BROUSSET P SELVES J DELSOL G MARIAME B
Citation
F. Meggetto et al., REED-STERNBERG CELLS AND BYSTANDER LYMPHOCYTES IN LYMPH-NODES AFFECTED BY HODGKINS-DISEASE ARE INFECTED WITH DIFFERENT STRAINS OF EPSTEIN-BARR-VIRUS, Journal of virology, 71(3), 1997, pp. 2547-2549
Citations number
23
Categorie Soggetti
Virology
Journal title
Journal of virology → ACNP
ISSN journal
0022538X
Volume
71
Issue
3
Year of publication
1997
Pages
2547 - 2549
Database
ISI
SICI code
0022-538X(1997)71:3<2547:RCABLI>2.0.ZU;2-S
Abstract
In most cases of Epstein-Barr virus (EBV)-associated Hodgkin's disease (HD), EBV-positive Reed-Sternberg (RS) cells and rare EBV-positive re servoir lymphocytes coexist in lymph nodes. Here we show that, in two cases of EBV-associated HD, strains infecting RS cells and reservoir l ymphocytes of the same patient have different BNLF-1 genes. This sugge sts that RS cells and reservoir lymphocytes of the same patient are in fected by different EBV strains.