Wt. Lankes et al., CLONING AND SEQUENCING OF PORCINE MOESIN AND RADIXIN CDNA AND IDENTIFICATION OF HIGHLY CONSERVED DOMAINS, Biochimica et biophysica acta, 1216(3), 1993, pp. 479-482
The full length cDNA of porcine moesin and radixin have been cloned an
d sequenced. Comparison of the closely related sequences of human, mur
ine and porcine moesin, ezrin and radixin with a protein from Echinoco
ccus multilocularis, an evolutionarily quite distant human parasite, r
eveals several highly invariant domains in the aminoterminal and carbo
xyterminal regions. Most of these conserved domains are clustered arou
nd tyrosine residues that are putative phosphorylation sites for tyros
ine phosphokinases.