J. Depablos et al., LARGE EXPERIMENTAL SEGMENTAL BONE DEFECTS TREATED BY BONE TRANSPORTATION WITH MONOLATERAL EXTERNAL DISTRACTERS, Clinical orthopaedics and related research, (298), 1994, pp. 259-265
Monolateral frames were applied to five dogs and ten lambs for treatme
nt of large segmental bone defects (LSBD) surgically induced in one of
their femoral diaphyses. Reconstruction was attempted by bone transpo
rt, as developed by Ilizarov. Monolateral frames were used to minimize
the drawbacks of Ilizarov's circular device. Radiographic, computed t
omographic, and histologic studies were performed. The skin and soft t
issues were not a major obstacle for the longitudinal migration of the
screws during bone transport. Four months after the operations, heali
ng and remodeling of the bone defect was always satisfactory. Histolog
ically, the repair of the lengthened segment followed an intramembrano
us ossification pattern in its central areas and in the periphery as w
ell. At the end of the experiment, the new induced bone had a virtuall
y normal diaphyseal bone appearance. Bone transport for the treatment
of experimental LSBD can be completed in monolateral frames.