A 55 year old female with a history of three different malignancies in
cluding a cerebral glioblastoma developed two bone metastases (in the
spine and iliac crest). Histologic and immunohistochemical studies of
biopsy specimens demonstrated the presence of glial fibrillary acidic
protein, establishing that the bone tumors were metastases from the gl
ioblastoma. Specific features of these rare metastases are discussed.