Patellofemoral joint pain is one of the most common ailments associate
d with visits to sports medicine clinics and can be disabling, althoug
h conservative clinical treatment has a reportedly very high success r
ate. Patellofemoral joint pain is often associated with improper track
ing of the patella within the femoral trochlear notch. Improper tracki
ng of the patella can be associated with increased patellofemoral cont
act pressures that may be a mechanical stimulus underlying patellar ca
rtilage degeneration. In those cases in which anatomic anomalies and t
rauma may be excluded as the basis for improper tracking, attention is
directed toward possible disruptions to the central nervous system co
ntrol and contractile potential of the knee joint extensor musculature
that underlies proper patellofemoral mechanics. This paper presents a
review of three seminal components related to the neuromechanics of p
atellofemoral function; patellofemoral tracking, patellofemoral contac
t pressures, and neuromotor control of patellofemoral agonists. It is
the intent of the authors to illuminate areas requiring further basic
and clinical research and provide a point of departure for this work.