Rd. Carpenter et al., ANESTHESIA FOR INSERTION OF EAR TUBES IN CHILDREN COMPARISON OF PROPOFOL, THIOPENTONE AND HALOTHANE, Paediatric anaesthesia, 7(1), 1997, pp. 25-31
To determine the quality of anaesthesia and speed of recovery after pr
opofol anaesthesia for myringotomy in children, 100 children 2-12 year
s were randomized to one of four anaesthetic regimens for induction/ma
intenance: thiopentone (STP) (5 mg . kg(-1))/halothane, propofol (3 mg
. kg(-1))/halothane, halothane/halothane or propofol (3 mg . kg(-1))/
propofol bolus (0.5 mg . kg(-1) every 3 min (10 mg . kg(-1). h(-1))).
Nitrous oxide (70%) in oxygen (30%) was used to facilitate insertion o
f an intravenous catheter and was continued throughout the anaesthetic
. We found that the incidence of intraoperative movement in response t
o surgical stimulation was significantly greater in the prop/prop grou
p 32%, compared with the three other groups (P<0.02). Although some re
covery variables (time to response to questions, sit unaided, tolerate
oral fluids, and discharge with fluids) were achieved more rapidly by
the prop/prop group than the other three groups, the times to open ey
es, obey commands and, most importantly, discharge from recovery witho
ut fluids did not differ between the prop/prop and the hal/hal groups.
We conclude that there is little benefit in using propofol as an indu
ction agent alone or in combination with a propofol maintenance anaest
hetic for paediatric myringotomy and tube surgery.