SELF-REGENERATING BONE IMPLANT - ECTOPIC OSTEOINDUCTION FOLLOWING INTRAMUSCULAR IMPLANTATION OF A COMBINATION OF RHBMP-2 ATELOPEPTIDE TYPE-I COLLAGEN AND POROUS HYDROXYAPATITE

Authors
KUSUMOTO K BESSHO K FUJIMURA K KONISHI Y OGAWA Y IIZUKA T
Citation
K. Kusumoto et al., SELF-REGENERATING BONE IMPLANT - ECTOPIC OSTEOINDUCTION FOLLOWING INTRAMUSCULAR IMPLANTATION OF A COMBINATION OF RHBMP-2 ATELOPEPTIDE TYPE-I COLLAGEN AND POROUS HYDROXYAPATITE, Journal of cranio-maxillo-facial surgery, 24(6), 1996, pp. 360-365
Citations number
18
Categorie Soggetti
Dentistry,Oral Surgery & Medicine",Surgery
Journal title
Journal of cranio-maxillo-facial surgery → ACNP
ISSN journal
10105182
Volume
24
Issue
6
Year of publication
1996
Pages
360 - 365
Database
ISI
SICI code
1010-5182(1996)24:6<360:SBI-EO>2.0.ZU;2-Q
Abstract
A combination of recombinant human bone morphogenetic protein-2 (rhBMP -2), atelopeptide Type I collagen (CL) as a carrier and porous hydroxy apatite (pHAP) was implanted in a calf muscle pouch of the rat. Three rhBMP-2-implanted groups (2, 10 and 50 mu g; each n=5) and the control group (n=5), in which only CL and pHAP were implanted, were establish ed. Three weeks later, the implants were examined.