PHASE-BEHAVIOR OF AQUEOUS SYSTEMS OF ENZYMATICALLY MODIFIED PHOSPHATIDYLCHOLINES WITH ONE HEXADECYL AND ONE HEXYL OR OCTYL CHAIN

Authors
SVENSSON I ADLERCREUTZ P MATTIASSON B MIESIZ Y LARSSON K
Citation
I. Svensson et al., PHASE-BEHAVIOR OF AQUEOUS SYSTEMS OF ENZYMATICALLY MODIFIED PHOSPHATIDYLCHOLINES WITH ONE HEXADECYL AND ONE HEXYL OR OCTYL CHAIN, Chemistry and physics of lipids, 66(3), 1993, pp. 195-197
Citations number
7
Categorie Soggetti
Biology
Journal title
Chemistry and physics of lipids → ACNP
ISSN journal
00093084
Volume
66
Issue
3
Year of publication
1993
Pages
195 - 197
Database
ISI
SICI code
0009-3084(1993)66:3<195:POASOE>2.0.ZU;2-8
Abstract
Phosphatidylcholines composed of a hexadecyl chain in the 2-position a nd a hexyl or octyl chain in the 1-position (C6C16PC Or C8C16PC) were prepared from dipalmitoylphosphatidylcholine by lipase-catalyzed trans esterification; the aqueous phase properties of the products were exam ined. In the C8C16PC-water system, a lamellar liquid-crystalline phase was dominant. Like all long-chain phosphatidylcholines studied earlie r, a liposomal dispersion was formed in the presence of excess water. In the C6C16PC system, a new type of phase behaviour was observed; at high water content, an L(3) phase was formed.