The mechanism by which western equine encephalomyelitis (WEE) virus an
d other mosquito-borne alphaviruses (Togaviridae) survive during perio
ds of vector inactivity is unknown. Recently, three strains of WEE vir
us were isolated from adult Aedes dorsalis collected as larvae from a
salt marsh in a coastal region of California. This provides evidence o
f vertical transmission of WEE virus in mosquitoes in nature. Vertical
transmission in Ae. dorsalis and closely related mosquito species may
be an important mechanism for the maintenance of WEE virus in tempera
te regions in North America where horizontal transmission of the virus
is seasonal.