INTERFERON-GAMMA PRODUCTION SPECIFIC FOR HEPATITIS-B VIRUS-ANTIGEN BYINTRAHEPATIC T-LYMPHOCYTES IN PATIENTS WITH ACUTE AND CHRONIC HEPATITIS-B

Authors
KAKUMU S ISHIKAWA T WAKITA T YOSHIOKA K TAKAYANAGI M TAHARA H KUSAKABE A
Citation
S. Kakumu et al., INTERFERON-GAMMA PRODUCTION SPECIFIC FOR HEPATITIS-B VIRUS-ANTIGEN BYINTRAHEPATIC T-LYMPHOCYTES IN PATIENTS WITH ACUTE AND CHRONIC HEPATITIS-B, The American journal of gastroenterology, 89(1), 1994, pp. 92-96
Citations number
18
Categorie Soggetti
Gastroenterology & Hepatology
Journal title
The American journal of gastroenterology → ACNP
ISSN journal
00029270
Volume
89
Issue
1
Year of publication
1994
Pages
92 - 96
Database
ISI
SICI code
0002-9270(1994)89:1<92:IPSFHV>2.0.ZU;2-N
Abstract
Objectives: Studies were undertaken to determine whether intrahepatic lymphocytes have a greater cellular immune response specific for hepat itis B virus (HBV) antigen than peripheral blood lymphocytes in HBV- i nfected man. Methods: HB nucleocapsid antigen-stimulated interferon-ga mma (IFN-gamma) production of lymphocytes was measured in acute self-l imited hepatitis (AH) (eight cases) and chronic hepatitis (CH) (14 cas es).