ON LINE CONTINUOUS MONITORING OF BLOOD LACTATE IN MEN BY A WEARABLE DEVICE BASED UPON AN ENZYMATIC AMPEROMETRIC LACTATE SENSOR

A wearable device for the continuous measurement of lactate in the blo od was constructed by the combination of continuous blood sampling emp loying a double lumen catheter with an amperometric lactate sensor. In vitro, the lactate sensor turned out to have a linear concentration r ange between 0 and 15 mmol/l. The response time of the sensor itself a mounted to 100 sec, whereas the lag time for blood sampling amounted t o 2.2 min. In vivo, the lactate sensor was successfully used for the d etection of changes of the blood lactate concentration following stren uous exercise in 7 healthy volunteers, in two cases up to 22 h. In con clusion, the technique of continuous blood sampling by the use of a do uble lumen catheter in combination with the amperometric lactate senso r is feasible and simplifies frequent blood lactate estimations.