S. Leistner et S. Dumke, 1,3-BIS(PYRIDIN-2-YLTHIO)PROPAN-2-ONES, B IS(THIENO[2,3-B]PYRIDIN-2-YL)KETONES AND 5H-BISPYRIDO[3',2' 4,5]THIENO[2,3-B/2',3'-E]PYRIDIN-11-ONES/, Archiv der pharmazie, 326(12), 1993, pp. 959-961
Reaction of 1a-d with 1,3-dichloroacetone gives the bissulphides 2a-d.
Base catalyzed cyclization of 2a-d affords heterocyclically substitut
ed ketones 3a-e. Treatment of 3a and 3b in cone. H,PO, leads to the bi
spyridothienopyridines 5a and 5b.