EFFICIENCY OF AN AUTOMATIC PEAK PURITY CONTROL PROCEDURE IN HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY PHOTODIODE-ARRAY COUPLING BASED ON EVOLVING FACTOR-ANALYSIS

Authors
GILLIARD JA CUMPS JL TILQUIN BL
Citation
Ja. Gilliard et al., EFFICIENCY OF AN AUTOMATIC PEAK PURITY CONTROL PROCEDURE IN HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY PHOTODIODE-ARRAY COUPLING BASED ON EVOLVING FACTOR-ANALYSIS, Chemometrics and intelligent laboratory systems, 21(2-3), 1993, pp. 235-242
Citations number
14
Categorie Soggetti
Computer Application, Chemistry & Engineering","Instument & Instrumentation","Chemistry Analytical","Computer Science Artificial Intelligence","Robotics & Automatic Control
Journal title
Chemometrics and intelligent laboratory systems → ACNP
ISSN journal
01697439
Volume
21
Issue
2-3
Year of publication
1993
Pages
235 - 242
Database
ISI
SICI code
0169-7439(1993)21:2-3<235:EOAAPP>2.0.ZU;2-M
Abstract
A modified version of evolving factor analysis, a fully multivariate t echnique promising to check peak purity in liquid chromatography with photodiode array detection, has been commercially implemented. The cap abilities of the algorithm are tested on actual chromatographic data. The results may be regarded as quite remarkable considering that no pr ior information about the solutes is necessary. When using the algorit hm, one has however to be aware that the maximal absorbance must be ke pt lower than 0.4 AU and that a data rate of 1 Hz is required for opti mal peak purity assignment, as a result of the influence of non-consta nt variance and scattering of the spectral data on the computation tec hnique.