In our department, a new compact and atraumatic centrifugal pump, Nikk
iso, was developed as a second-generation cardiopulmonary bypass pump.
To assess and confirm the function and controllability of this pump,
comparative studies of cardiopulmonary bypass with Nikkiso and BioMedi
cus centrifugal pumps were performed using calves. Both pumps provided
pump flows of 60-70 ml/kg/min without incidence. The hemodynamics of
both groups were stable and within the normal range, and no leakage or
thrombus formations were observed in either pump. All hematology and
biochemistry data showed no significant differences between the two gr
oups. Plasma free hemoglobin values of the Nikkiso pump tended to be l
ower than those of the BioMedicus pump. The Nikkiso pump was easy to h
andle because of its smaller size, and air removal was easily performe
d because of its low priming volume. The Nikkiso pump demonstrated eas
y manipulation and good controllability. This compact, atraumatic cent
rifugal pump meets the requirements for a second-generation cardiopulm
onary by-pass pump.