SUCCESSFUL TREATMENT OF HIV-RELATED VASCULITIS WITH PERIPHERAL NEUROPATHY WITH SHORT-TERM STEROIDS FOLLOWED BY THE ASSOCIATION OF ZIDOVUDINE AND PLASMAPHERESIS

Objective-treatment of HIV-related vasculitis, avoiding prolonged immu nosuppressive therapy. Design-prospective pilot study of HIV-related n eurological vasculitis. Patients-two HIV-infected patients with histol ogically proven vasculitis. Intervention-short-term corticosteroid fol lowed by zidovudine combined with plasmapheresis. Main outcome measure s-clinical, biological, immunological and electromyographic evaluation . Results-complete neurological recovery. Conclusions-excellent tolera nce and efficacy of combined zidovudine and plasmapheresis therapy in peripheral neurological HIV-related vasculitis.