PARTICIPATION OF INDUCIBLE STRESS PROTEINS IN THE CARDIOPROTECTIVE EFFECT OF RHODIOLAE-ROSEA

Authors
AFANASEV SA KRYLATOV AV LASUKOVA TV LISHMANOV YB
Citation
Sa. Afanasev et al., PARTICIPATION OF INDUCIBLE STRESS PROTEINS IN THE CARDIOPROTECTIVE EFFECT OF RHODIOLAE-ROSEA, Biochemistry, 61(10), 1996, pp. 1258-1261
Citations number
19
Categorie Soggetti
Biology
Journal title
Biochemistry → ACNP
ISSN journal
00062979
Volume
61
Issue
10
Year of publication
1996
Pages
1258 - 1261
Database
ISI
SICI code
0006-2979(1996)61:10<1258:POISPI>2.0.ZU;2-Q
Abstract
Effects of the Rhodiolae rosea extract on the contractility of rat hea rts isolated by the method of Langendorff, the activity of creatine ph osphokinase in the perfusate, and the induction of synthesis of stress proteins in the myocardium were studied after total ischemia and repe rfusion. This adaptogen produced a cardioprotective effect and prevent ed a disturbance of contractility due to ischemia and reperfusion. The possible participation of the inducible stress proteins (hsp-70) in t hese effects is discussed.